5 Sisters Nails & Spa
Try this look on your hands virtually! ✨
Nail Art AI picks
Shop the salon look
As an Amazon Associate, Nail Art AI earns from qualifying purchases. This comes at no additional cost to you.
🕐Opening Hours
Open NowToday (Sunday)
9:00 AM – 7:30 PM
🗺️Explore Salons in Other South Carolina Cities
Find nail salons in major cities across South Carolina
⭐Similar Quality Salons in South Carolina
Other highly-rated salons you might like
The Man Cave Nailcare for Gentlemen
Spartanburg, South Carolina
East Star Nail & Spa LLC
Spartanburg, South Carolina
Institute of Beauty Artistry - IBA Nail School & Nail Supply
Spartanburg, South Carolina
Capped Nails
Spartanburg, South Carolina
Southern Nails and Spa
Spartanburg, South Carolina
Paradise Nails & Spa llC
Spartanburg, South Carolina
🏆Top-Rated Salons in South Carolina
The best-reviewed nail salons across the state
Amazing Nails Spa JI
Charleston
May Nail Salon & Spa
Columbia
Otani Nails,Brow Waxing & Studio Suites
Richland
J&V Nail Spa
Charleston
Lust Nails and Spa
Columbia
Nail Inspiration Studios LLC
Charleston
The Nail House LLC
Columbia
Nails Inspiration Spa
Charleston
💅 Nail Art Design Inspiration
Get inspired by these stunning nail art designs! Show these to the talented artists at 5 Sisters Nails & Spa to recreate your perfect look.
French Cobalt Blue Chrome Blue Nails
Blue Glazed Donut Glossy Blue Nails
Beautiful Photo-real Salon Chevron Nails
Blue Watercolor White Swirls Blue Nails
French Cobalt Blue Chrome Blue Nails
Navy Blue Gold Foil Blue Nails
Blue Glazed Donut Glossy Blue Nails
Gorgeous Photo-real Salon Chevron Nails
Love these designs? Browse thousands more in our gallery!
📚 Design Collections
Explore curated collections of nail art designs. Perfect for special occasions and themed looks at 5 Sisters Nails & Spa.
🎨 Color Palette Recommendations
Discover stunning color combinations perfect for your next manicure at 5 Sisters Nails & Spa. Each palette showcases designs that work beautifully together.
✨ Specialty Techniques
Discover professional nail art techniques mastered by the talented artists at 5 Sisters Nails & Spa. Each technique showcases the skill and artistry available at our salon.
Trending Fall Nail Designs
Discover the hottest nail art trends for fall 2026. The talented team at 5 Sisters Nails & Spa stays up-to-date with seasonal styles to keep your nails on-trend.
Autumn Leaves
Warm oranges, reds, and yellows with leaf motifs
Pumpkin Spice Colors
Burnt orange, cinnamon brown, and cream tones
Plaid Patterns
Cozy flannel-inspired designs in fall colors
Burgundy & Gold
Deep wine red with metallic gold accents
Harvest Moon
Warm metallic copper and bronze finishes
Ready for a Fall Makeover?
Book your appointment and ask about our seasonal specials!
At-Home Nail Care Routine
Expert advice from the professionals at 5 Sisters Nails & Spa
- ✓Soak nails in warm water with a few drops of olive oil for 10 minutes weekly
- ✓Gently buff nail surface to smooth ridges and improve polish adhesion
- ✓Apply cuticle oil before bed and massage into nails and skin
- ✓Ask 5 Sisters Nails & Spa to recommend the best nail strengthener for your nail type
- ✓Keep a nail file handy to smooth any snags immediately
💎 Pro Tip: Maintain your professional results from 5 Sisters Nails & Spa with a weekly at-home spa treatment between salon visits!
🏷️ Explore Nail Art by Tags
Browse our gallery by colors, techniques, occasions, and styles. Show these ideas to the artists at 5 Sisters Nails & Spa!
Other Salons in Spartanburg
Southern Nails and Spa
2601 E Main St #18, Spartanburg, SC 29307
SA Nail & Spa
914 E Main St, Spartanburg, SC 29302
Bliss Nails & Spa
1855 E Main St #22, Spartanburg, SC 29307
Dorman Nail & Spa
131 Dorman Centre Dr # D, Spartanburg, SC 29301
Paradise Nails & Spa llC
140 Fernwood Dr # 3, Spartanburg, SC 29307
Data provided by Google Maps
📍Location
880 E Main St, Spartanburg, SC 29302
View on Google Maps→Quick Contact
At-home edit
Salon essentials
🕐Today's Hours
Monday: 9:00 AM – 7:30 PM
✓ Currently Open
Own 5 Sisters Nails & Spa?
Claim your listing to get featured placement, add photos, display your services, and attract more customers.
- ✓Get top placement in search results
- ✓"Featured" badge to stand out
- ✓Add photos, services & booking link
- ✓Monthly analytics on views & clicks
Visiting a salon? 💅
Try 1000+ designs virtually!